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Bronchoscopic valve placement for the treatment of persistent air leaks

Persistent air leaks (PALs) are associated with increased morbidity, prolonged hospital stay, and increased treatment costs. Endobronchial 1-way valves have been recently used as a potential less invasive treatment option. We sought to investigate the effects of valve therapy in treating this condit...

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Autores principales: Huang, Xiaojie, Ding, Liren, Xu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895398/
https://www.ncbi.nlm.nih.gov/pubmed/29595651
http://dx.doi.org/10.1097/MD.0000000000010183
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author Huang, Xiaojie
Ding, Liren
Xu, Hao
author_facet Huang, Xiaojie
Ding, Liren
Xu, Hao
author_sort Huang, Xiaojie
collection PubMed
description Persistent air leaks (PALs) are associated with increased morbidity, prolonged hospital stay, and increased treatment costs. Endobronchial 1-way valves have been recently used as a potential less invasive treatment option. We sought to investigate the effects of valve therapy in treating this condition. The patients with evidence of continuous air leak flow whose chest tubes remained in place for more than 7 days were treated with bronchoscopic closure using 1-way valves. The source of the air leak was identified by the Chartis system. A total of 11 patients (1 woman, 10 men; mean age, 68 years) who underwent valve placement were eligible to be enrolled from January 2015 through January 2017. Six patients had postoperative PAL, and 5 had a secondary spontaneous pneumothorax. The number of used valves varied from 1 to 3 (median 1). The resolution of the leak was complete in 8 patients (72.7%), whose mean duration of air leak before and after valve deployment was 58.5 and 4.5 days, respectively. There were no complications related to the valve deployment. Bronchoscopic placement of 1-way valves is a safe procedure that could help manage patients with prolonged PALs. A prospective randomized trial with cost-efficiency analysis is necessary to better define the role of this bronchoscopic intervention and demonstrate its effect on air leak duration.
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spelling pubmed-58953982018-04-18 Bronchoscopic valve placement for the treatment of persistent air leaks Huang, Xiaojie Ding, Liren Xu, Hao Medicine (Baltimore) 6700 Persistent air leaks (PALs) are associated with increased morbidity, prolonged hospital stay, and increased treatment costs. Endobronchial 1-way valves have been recently used as a potential less invasive treatment option. We sought to investigate the effects of valve therapy in treating this condition. The patients with evidence of continuous air leak flow whose chest tubes remained in place for more than 7 days were treated with bronchoscopic closure using 1-way valves. The source of the air leak was identified by the Chartis system. A total of 11 patients (1 woman, 10 men; mean age, 68 years) who underwent valve placement were eligible to be enrolled from January 2015 through January 2017. Six patients had postoperative PAL, and 5 had a secondary spontaneous pneumothorax. The number of used valves varied from 1 to 3 (median 1). The resolution of the leak was complete in 8 patients (72.7%), whose mean duration of air leak before and after valve deployment was 58.5 and 4.5 days, respectively. There were no complications related to the valve deployment. Bronchoscopic placement of 1-way valves is a safe procedure that could help manage patients with prolonged PALs. A prospective randomized trial with cost-efficiency analysis is necessary to better define the role of this bronchoscopic intervention and demonstrate its effect on air leak duration. Wolters Kluwer Health 2018-03-30 /pmc/articles/PMC5895398/ /pubmed/29595651 http://dx.doi.org/10.1097/MD.0000000000010183 Text en Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. http://creativecommons.org/licenses/by-nc-sa/4.0
spellingShingle 6700
Huang, Xiaojie
Ding, Liren
Xu, Hao
Bronchoscopic valve placement for the treatment of persistent air leaks
title Bronchoscopic valve placement for the treatment of persistent air leaks
title_full Bronchoscopic valve placement for the treatment of persistent air leaks
title_fullStr Bronchoscopic valve placement for the treatment of persistent air leaks
title_full_unstemmed Bronchoscopic valve placement for the treatment of persistent air leaks
title_short Bronchoscopic valve placement for the treatment of persistent air leaks
title_sort bronchoscopic valve placement for the treatment of persistent air leaks
topic 6700
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895398/
https://www.ncbi.nlm.nih.gov/pubmed/29595651
http://dx.doi.org/10.1097/MD.0000000000010183
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