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Distributed hepatocytes expressing telomerase repopulate the liver in homeostasis and injury

Hepatocytes are replenished gradually during homeostasis and robustly after liver injury(1,2). In adults, new hepatocytes originate from the existing hepatocyte pool(3-8), but the cellular source of renewing hepatocytes remains incompletely understood. Telomerase is expressed in many stem cell popul...

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Detalles Bibliográficos
Autores principales: Lin, Shengda, Nascimento, Elisabete M., Gajera, Chandresh, Chen, Lu, Neuhoefer, Patrick, Garbuzov, Alina, Wang, Sui, Artandi, Steven E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895494/
https://www.ncbi.nlm.nih.gov/pubmed/29618815
http://dx.doi.org/10.1038/s41586-018-0004-7