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Distributed hepatocytes expressing telomerase repopulate the liver in homeostasis and injury
Hepatocytes are replenished gradually during homeostasis and robustly after liver injury(1,2). In adults, new hepatocytes originate from the existing hepatocyte pool(3-8), but the cellular source of renewing hepatocytes remains incompletely understood. Telomerase is expressed in many stem cell popul...
Autores principales: | Lin, Shengda, Nascimento, Elisabete M., Gajera, Chandresh, Chen, Lu, Neuhoefer, Patrick, Garbuzov, Alina, Wang, Sui, Artandi, Steven E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895494/ https://www.ncbi.nlm.nih.gov/pubmed/29618815 http://dx.doi.org/10.1038/s41586-018-0004-7 |
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