ROS release by PPARβ/δ-null fibroblasts reduces tumor load through epithelial antioxidant response

Tumor stroma has an active role in the initiation, growth, and propagation of many tumor types by secreting growth factors and modulating redox status of the microenvironment. Although PPARβ/δ in fibroblasts was shown to modulate oxidative stress in the wound microenvironment, there has been no evid...

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Detalles Bibliográficos
Autores principales: Tan, Eddie Han Pin, Sng, Ming Keat, How, Ivan Shun Bo, Chan, Jeremy Soon Kiat, Chen, Jiapeng, Tan, Chek Kun, Wahli, Walter, Tan, Nguan Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895604/
https://www.ncbi.nlm.nih.gov/pubmed/29367760
http://dx.doi.org/10.1038/s41388-017-0109-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895604/
https://www.ncbi.nlm.nih.gov/pubmed/29367760
http://dx.doi.org/10.1038/s41388-017-0109-8

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