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Network analysis of SRC-1 reveals a novel transcription factor hub which regulates endocrine resistant breast cancer
Steroid receptor coactivator 1 (SRC-1) interacts with nuclear receptors and other transcription factors (TFs) to initiate transcriptional networks and regulate downstream genes which enable the cancer cell to evade therapy and metastasise. Here we took a top–down discovery approach to map out the SR...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895607/ https://www.ncbi.nlm.nih.gov/pubmed/29367763 http://dx.doi.org/10.1038/s41388-017-0042-x |