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Network analysis of SRC-1 reveals a novel transcription factor hub which regulates endocrine resistant breast cancer

Steroid receptor coactivator 1 (SRC-1) interacts with nuclear receptors and other transcription factors (TFs) to initiate transcriptional networks and regulate downstream genes which enable the cancer cell to evade therapy and metastasise. Here we took a top–down discovery approach to map out the SR...

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Detalles Bibliográficos
Autores principales:	Browne, Alacoque L., Charmsaz, Sara, Varešlija, Damir, Fagan, Ailis, Cosgrove, Nicola, Cocchiglia, Sinéad, Purcell, Siobhan, Ward, Elspeth, Bane, Fiona, Hudson, Lance, Hill, Arnold D., Carroll, Jason S., Redmond, Aisling M., Young, Leonie S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895607/ https://www.ncbi.nlm.nih.gov/pubmed/29367763 http://dx.doi.org/10.1038/s41388-017-0042-x

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