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The role of stabilizing and communicating symptoms given overlapping communities in psychopathology networks

Network theory, as a theoretical and methodological framework, is energizing many research fields, among which clinical psychology and psychiatry. Fundamental to the network theory of psychopathology is the role of specific symptoms and their interactions. Current statistical tools, however, fail to...

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Autores principales: Blanken, Tessa F., Deserno, Marie K., Dalege, Jonas, Borsboom, Denny, Blanken, Peter, Kerkhof, Gerard A., Cramer, Angélique O. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895626/
https://www.ncbi.nlm.nih.gov/pubmed/29643399
http://dx.doi.org/10.1038/s41598-018-24224-2
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author Blanken, Tessa F.
Deserno, Marie K.
Dalege, Jonas
Borsboom, Denny
Blanken, Peter
Kerkhof, Gerard A.
Cramer, Angélique O. J.
author_facet Blanken, Tessa F.
Deserno, Marie K.
Dalege, Jonas
Borsboom, Denny
Blanken, Peter
Kerkhof, Gerard A.
Cramer, Angélique O. J.
author_sort Blanken, Tessa F.
collection PubMed
description Network theory, as a theoretical and methodological framework, is energizing many research fields, among which clinical psychology and psychiatry. Fundamental to the network theory of psychopathology is the role of specific symptoms and their interactions. Current statistical tools, however, fail to fully capture this constitutional property. We propose community detection tools as a means to evaluate the complex network structure of psychopathology, free from its original boundaries of distinct disorders. Unique to this approach is that symptoms can belong to multiple communities. Using a large community sample and spanning a broad range of symptoms (Symptom Checklist-90-Revised), we identified 18 communities of interconnected symptoms. The differential role of symptoms within and between communities offers a framework to study the clinical concepts of comorbidity, heterogeneity and hallmark symptoms. Symptoms with many and strong connections within a community, defined as stabilizing symptoms, could be thought of as the core of a community, whereas symptoms that belong to multiple communities, defined as communicating symptoms, facilitate the communication between problem areas. We propose that defining symptoms on their stabilizing and/or communicating role within and across communities accelerates our understanding of these clinical phenomena, central to research and treatment of psychopathology.
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spelling pubmed-58956262018-04-20 The role of stabilizing and communicating symptoms given overlapping communities in psychopathology networks Blanken, Tessa F. Deserno, Marie K. Dalege, Jonas Borsboom, Denny Blanken, Peter Kerkhof, Gerard A. Cramer, Angélique O. J. Sci Rep Article Network theory, as a theoretical and methodological framework, is energizing many research fields, among which clinical psychology and psychiatry. Fundamental to the network theory of psychopathology is the role of specific symptoms and their interactions. Current statistical tools, however, fail to fully capture this constitutional property. We propose community detection tools as a means to evaluate the complex network structure of psychopathology, free from its original boundaries of distinct disorders. Unique to this approach is that symptoms can belong to multiple communities. Using a large community sample and spanning a broad range of symptoms (Symptom Checklist-90-Revised), we identified 18 communities of interconnected symptoms. The differential role of symptoms within and between communities offers a framework to study the clinical concepts of comorbidity, heterogeneity and hallmark symptoms. Symptoms with many and strong connections within a community, defined as stabilizing symptoms, could be thought of as the core of a community, whereas symptoms that belong to multiple communities, defined as communicating symptoms, facilitate the communication between problem areas. We propose that defining symptoms on their stabilizing and/or communicating role within and across communities accelerates our understanding of these clinical phenomena, central to research and treatment of psychopathology. Nature Publishing Group UK 2018-04-11 /pmc/articles/PMC5895626/ /pubmed/29643399 http://dx.doi.org/10.1038/s41598-018-24224-2 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Blanken, Tessa F.
Deserno, Marie K.
Dalege, Jonas
Borsboom, Denny
Blanken, Peter
Kerkhof, Gerard A.
Cramer, Angélique O. J.
The role of stabilizing and communicating symptoms given overlapping communities in psychopathology networks
title The role of stabilizing and communicating symptoms given overlapping communities in psychopathology networks
title_full The role of stabilizing and communicating symptoms given overlapping communities in psychopathology networks
title_fullStr The role of stabilizing and communicating symptoms given overlapping communities in psychopathology networks
title_full_unstemmed The role of stabilizing and communicating symptoms given overlapping communities in psychopathology networks
title_short The role of stabilizing and communicating symptoms given overlapping communities in psychopathology networks
title_sort role of stabilizing and communicating symptoms given overlapping communities in psychopathology networks
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895626/
https://www.ncbi.nlm.nih.gov/pubmed/29643399
http://dx.doi.org/10.1038/s41598-018-24224-2
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