Emergence of Relaxation Oscillations in Neurons Interacting With Non-stationary Ambient GABA

Dynamics of a homogeneous neural population interacting with active extracellular medium were considered. The corresponding mathematical model was tuned specifically to describe the behavior of interneurons with tonic GABA conductance under the action of non-stationary ambient GABA. The feedback pro...

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Autores principales: Adamchik, Denis A., Matrosov, Valery V., Kazantsev, Victor B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895729/
https://www.ncbi.nlm.nih.gov/pubmed/29674960
http://dx.doi.org/10.3389/fncom.2018.00019
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author Adamchik, Denis A.
Matrosov, Valery V.
Kazantsev, Victor B.
author_facet Adamchik, Denis A.
Matrosov, Valery V.
Kazantsev, Victor B.
author_sort Adamchik, Denis A.
collection PubMed
description Dynamics of a homogeneous neural population interacting with active extracellular medium were considered. The corresponding mathematical model was tuned specifically to describe the behavior of interneurons with tonic GABA conductance under the action of non-stationary ambient GABA. The feedback provided by the GABA mediated transmembrane current enriched the repertoire of population activity by enabling the oscillatory behavior. This behavior appeared in the form of relaxation oscillations which can be considered as a specific type of brainwaves.
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spelling pubmed-58957292018-04-19 Emergence of Relaxation Oscillations in Neurons Interacting With Non-stationary Ambient GABA Adamchik, Denis A. Matrosov, Valery V. Kazantsev, Victor B. Front Comput Neurosci Neuroscience Dynamics of a homogeneous neural population interacting with active extracellular medium were considered. The corresponding mathematical model was tuned specifically to describe the behavior of interneurons with tonic GABA conductance under the action of non-stationary ambient GABA. The feedback provided by the GABA mediated transmembrane current enriched the repertoire of population activity by enabling the oscillatory behavior. This behavior appeared in the form of relaxation oscillations which can be considered as a specific type of brainwaves. Frontiers Media S.A. 2018-04-05 /pmc/articles/PMC5895729/ /pubmed/29674960 http://dx.doi.org/10.3389/fncom.2018.00019 Text en Copyright © 2018 Adamchik, Matrosov and Kazantsev. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Adamchik, Denis A.
Matrosov, Valery V.
Kazantsev, Victor B.
Emergence of Relaxation Oscillations in Neurons Interacting With Non-stationary Ambient GABA
title Emergence of Relaxation Oscillations in Neurons Interacting With Non-stationary Ambient GABA
title_full Emergence of Relaxation Oscillations in Neurons Interacting With Non-stationary Ambient GABA
title_fullStr Emergence of Relaxation Oscillations in Neurons Interacting With Non-stationary Ambient GABA
title_full_unstemmed Emergence of Relaxation Oscillations in Neurons Interacting With Non-stationary Ambient GABA
title_short Emergence of Relaxation Oscillations in Neurons Interacting With Non-stationary Ambient GABA
title_sort emergence of relaxation oscillations in neurons interacting with non-stationary ambient gaba
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895729/
https://www.ncbi.nlm.nih.gov/pubmed/29674960
http://dx.doi.org/10.3389/fncom.2018.00019
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