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How single mutations affect viral escape from broad and narrow antibodies to H1 influenza hemagglutinin
Influenza virus can escape most antibodies with single mutations. However, rare antibodies broadly neutralize many viral strains. It is unclear how easily influenza virus might escape such antibodies if there was strong pressure to do so. Here, we map all single amino-acid mutations that increase re...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895760/ https://www.ncbi.nlm.nih.gov/pubmed/29643370 http://dx.doi.org/10.1038/s41467-018-03665-3 |