Sialidase Deficiency in Porphyromonas gingivalis Increases IL-12 Secretion in Stimulated Macrophages Through Regulation of CR3, IncRNA GAS5 and miR-21

Porphyromonas gingivalis (P. gingivalis) is a major periodontal pathogen that can induce an immune response leading to a destructive inflammatory process. During the inflammatory process, interleukin-12 (IL-12) is secreted, correlating with bacterial clearance by macrophages. Bacterial sialidase has...

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Detalles Bibliográficos
Autores principales: Yang, Xue, Pan, Yaping, Xu, Xiaoyu, Tong, Tong, Yu, Shiwen, Zhao, Yue, Lin, Li, Liu, Jingbo, Zhang, Dongmei, Li, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895773/
https://www.ncbi.nlm.nih.gov/pubmed/29675399
http://dx.doi.org/10.3389/fcimb.2018.00100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895773/
https://www.ncbi.nlm.nih.gov/pubmed/29675399
http://dx.doi.org/10.3389/fcimb.2018.00100

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