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Sialidase Deficiency in Porphyromonas gingivalis Increases IL-12 Secretion in Stimulated Macrophages Through Regulation of CR3, IncRNA GAS5 and miR-21
Porphyromonas gingivalis (P. gingivalis) is a major periodontal pathogen that can induce an immune response leading to a destructive inflammatory process. During the inflammatory process, interleukin-12 (IL-12) is secreted, correlating with bacterial clearance by macrophages. Bacterial sialidase has...
Autores principales: | Yang, Xue, Pan, Yaping, Xu, Xiaoyu, Tong, Tong, Yu, Shiwen, Zhao, Yue, Lin, Li, Liu, Jingbo, Zhang, Dongmei, Li, Chen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895773/ https://www.ncbi.nlm.nih.gov/pubmed/29675399 http://dx.doi.org/10.3389/fcimb.2018.00100 |
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