Development by Genetic Immunization of Monovalent Antibodies Against Human Vasoactive Intestinal Peptide Receptor 1 (VPAC1), New Innovative, and Versatile Tools to Study VPAC1 Receptor Function

Multi-membrane spanning proteins, such as G protein-coupled receptors (GPCRs) and ion channels, are extremely difficult to purify as native proteins. Consequently, the generation of antibodies that recognize the native conformation can be challenging. By combining genetic immunization, phage display...

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Detalles Bibliográficos
Autores principales: Peyrassol, Xavier, Laeremans, Toon, Lahura, Vannessa, Debulpaep, Maja, El Hassan, Hassan, Steyaert, Jan, Parmentier, Marc, Langer, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895782/
https://www.ncbi.nlm.nih.gov/pubmed/29674997
http://dx.doi.org/10.3389/fendo.2018.00153

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