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Peripherally Administered Y(2)-Receptor Antagonist BIIE0246 Prevents Diet-Induced Obesity in Mice With Excess Neuropeptide Y, but Enhances Obesity in Control Mice
Neuropeptide Y (NPY) plays an important role in the regulation of energy homeostasis in the level of central and sympathetic nervous systems (SNSs). Genetic silencing of peripheral Y(2)-receptors have anti-obesity effects, but it is not known whether pharmacological blocking of peripheral Y(2)-recep...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895854/ https://www.ncbi.nlm.nih.gov/pubmed/29674968 http://dx.doi.org/10.3389/fphar.2018.00319 |