PI3K, p38 and JAK/STAT signalling in bronchial tissue from patients with asthma following allergen challenge

BACKGROUND: Inhaled allergen challenges are often used to evaluate novel asthma treatments in early phase clinical trials. Current novel therapeutic targets in asthma include phosphoinositide 3-kinases (PI3K) delta and gamma, p38 mitogen-activated protein kinase (p38) and Janus kinase/Signal Transdu...

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Detalles Bibliográficos
Autores principales: Southworth, Thomas, Mason, Sarah, Bell, Alan, Ramis, Isabel, Calbet, Marta, Domenech, Anna, Prats, Neus, Miralpeix, Montserrat, Singh, Dave
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896031/
https://www.ncbi.nlm.nih.gov/pubmed/29651336
http://dx.doi.org/10.1186/s40364-018-0128-9

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