Zidovudine ameliorates pathology in the mouse model of Duchenne muscular dystrophy via P2RX7 purinoceptor antagonism

Duchenne muscular dystrophy (DMD) is the most common inherited muscle disorder that causes severe disability and death of young men. This disease is characterized by progressive muscle degeneration aggravated by sterile inflammation and is also associated with cognitive impairment and low bone densi...

Descripción completa

Detalles Bibliográficos
Autores principales: Al-Khalidi, Rasha, Panicucci, Chiara, Cox, Paul, Chira, Natalia, Róg, Justyna, Young, Christopher N. J., McGeehan, Rhiannon E., Ambati, Kameshwari, Ambati, Jayakrishna, Zabłocki, Krzysztof, Gazzerro, Elisabetta, Arkle, Stephen, Bruno, Claudio, Górecki, Dariusz C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896059/
https://www.ncbi.nlm.nih.gov/pubmed/29642926
http://dx.doi.org/10.1186/s40478-018-0530-4

Ejemplares similares

Ejemplares similares