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Tracing the evolution of the heterotrimeric G protein α subunit in Metazoa

BACKGROUND: Heterotrimeric G proteins are fundamental signaling proteins composed of three subunits, Gα and a Gβγ dimer. The role of Gα as a molecular switch is critical for transmitting and amplifying intracellular signaling cascades initiated by an activated G protein Coupled Receptor (GPCR). Desp...

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Detalles Bibliográficos
Autores principales:	Lokits, A. D., Indrischek, H., Meiler, J., Hamm, H. E., Stadler, P. F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896119/ https://www.ncbi.nlm.nih.gov/pubmed/29642851 http://dx.doi.org/10.1186/s12862-018-1147-8

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