A Transcriptomic Signature of the Hypothalamic Response to Fasting and BDNF Deficiency in Prader-Willi Syndrome

Transcriptional analysis of brain tissue from people with molecularly defined causes of obesity may highlight disease mechanisms and therapeutic targets. We performed RNA sequencing of hypothalamus from individuals with Prader-Willi syndrome (PWS), a genetic obesity syndrome characterized by severe...

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Detalles Bibliográficos
Autores principales: Bochukova, Elena G., Lawler, Katherine, Croizier, Sophie, Keogh, Julia M., Patel, Nisha, Strohbehn, Garth, Lo, Kitty K., Humphrey, Jack, Hokken-Koelega, Anita, Damen, Layla, Donze, Stephany, Bouret, Sebastien G., Plagnol, Vincent, Farooqi, I. Sadaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896230/
https://www.ncbi.nlm.nih.gov/pubmed/29590610
http://dx.doi.org/10.1016/j.celrep.2018.03.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896230/
https://www.ncbi.nlm.nih.gov/pubmed/29590610
http://dx.doi.org/10.1016/j.celrep.2018.03.018

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