Complementary Tuning of Na(+) and K(+) Channel Gating Underlies Fast and Energy-Efficient Action Potentials in GABAergic Interneuron Axons

Fast-spiking, parvalbumin-expressing GABAergic interneurons (PV(+)-BCs) express a complex machinery of rapid signaling mechanisms, including specialized voltage-gated ion channels to generate brief action potentials (APs). However, short APs are associated with overlapping Na(+) and K(+) fluxes and...

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Detalles Bibliográficos
Autores principales: Hu, Hua, Roth, Fabian C., Vandael, David, Jonas, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896255/
https://www.ncbi.nlm.nih.gov/pubmed/29621485
http://dx.doi.org/10.1016/j.neuron.2018.02.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896255/
https://www.ncbi.nlm.nih.gov/pubmed/29621485
http://dx.doi.org/10.1016/j.neuron.2018.02.024

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