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Complementary Tuning of Na(+) and K(+) Channel Gating Underlies Fast and Energy-Efficient Action Potentials in GABAergic Interneuron Axons
Fast-spiking, parvalbumin-expressing GABAergic interneurons (PV(+)-BCs) express a complex machinery of rapid signaling mechanisms, including specialized voltage-gated ion channels to generate brief action potentials (APs). However, short APs are associated with overlapping Na(+) and K(+) fluxes and...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896255/ https://www.ncbi.nlm.nih.gov/pubmed/29621485 http://dx.doi.org/10.1016/j.neuron.2018.02.024 |