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The Relation between Sarcopenia and Mortality in Patients at Intensive Care Unit

BACKGROUND AND AIM: Psoas muscle area (PMA) can reflect the status of skeletal muscle in the whole body. It has been also reported that decreased PMA was associated with postoperative mortality or morbidity after several surgical procedures. In this study, we aimed to investigate the relation betwee...

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Autores principales: Toptas, Mehmet, Yalcin, Mazhar, Akkoc, İbrahim, Demir, Eren, Metin, Cagatay, Savas, Yildiray, Kalyoncuoglu, Muhsin, Can, Mehmet Mustafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896340/
https://www.ncbi.nlm.nih.gov/pubmed/29789798
http://dx.doi.org/10.1155/2018/5263208
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author Toptas, Mehmet
Yalcin, Mazhar
Akkoc, İbrahim
Demir, Eren
Metin, Cagatay
Savas, Yildiray
Kalyoncuoglu, Muhsin
Can, Mehmet Mustafa
author_facet Toptas, Mehmet
Yalcin, Mazhar
Akkoc, İbrahim
Demir, Eren
Metin, Cagatay
Savas, Yildiray
Kalyoncuoglu, Muhsin
Can, Mehmet Mustafa
author_sort Toptas, Mehmet
collection PubMed
description BACKGROUND AND AIM: Psoas muscle area (PMA) can reflect the status of skeletal muscle in the whole body. It has been also reported that decreased PMA was associated with postoperative mortality or morbidity after several surgical procedures. In this study, we aimed to investigate the relation between PMA and mortality in all age groups in intensive care unit (UNIT). MATERIALS AND METHOD: The study consists of 362 consecutive patients. The demographic characteristics of patients, indications for ICU hospitalization, laboratory parameters, and clinical parameters consist of mortality and length of stay, and surgery history was obtained from intensive care archive records. RESULTS: The mean age was 61.2 ± 18.2 years, and the percentage of female was 33.3%. The mean duration of stay was 10.3 ± 24.4 days. Exitus ratio, partial healing, and healing were 25%, 70%, and 5%, respectively. The mean right, left, and total PMA were 8.7 ± 3.6, 8.9 ± 3.4, and 17.6 ± 6.9, respectively. The left and total PMA averages of the nonoperation patients were statistically significantly lower (p = 0.021  p = 0.043). The mean PMA between the ex and recovered patients were statistically significantly lower (p = 0.001, p = 0.001, p < 0.001). Dyspnoea, renal insufficiency, COPD, transfusion rate, operation rate, ventilator needy, and mean duration of hospitalization were statistically significant higher in patients with exitus. There is a significant difference in operation types, anesthesia type, and clinic rates. CONCLUSION: Our data suggest that sarcopenia can be used to risk stratification in ICU patients. Future studies may use this technique to individualize postoperative interventions that may reduce the risk for an adverse discharge disposition related to critical illness, such as early mobilization, optimized nutritional support, and reduction of sedation and opioid dose.
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spelling pubmed-58963402018-05-22 The Relation between Sarcopenia and Mortality in Patients at Intensive Care Unit Toptas, Mehmet Yalcin, Mazhar Akkoc, İbrahim Demir, Eren Metin, Cagatay Savas, Yildiray Kalyoncuoglu, Muhsin Can, Mehmet Mustafa Biomed Res Int Research Article BACKGROUND AND AIM: Psoas muscle area (PMA) can reflect the status of skeletal muscle in the whole body. It has been also reported that decreased PMA was associated with postoperative mortality or morbidity after several surgical procedures. In this study, we aimed to investigate the relation between PMA and mortality in all age groups in intensive care unit (UNIT). MATERIALS AND METHOD: The study consists of 362 consecutive patients. The demographic characteristics of patients, indications for ICU hospitalization, laboratory parameters, and clinical parameters consist of mortality and length of stay, and surgery history was obtained from intensive care archive records. RESULTS: The mean age was 61.2 ± 18.2 years, and the percentage of female was 33.3%. The mean duration of stay was 10.3 ± 24.4 days. Exitus ratio, partial healing, and healing were 25%, 70%, and 5%, respectively. The mean right, left, and total PMA were 8.7 ± 3.6, 8.9 ± 3.4, and 17.6 ± 6.9, respectively. The left and total PMA averages of the nonoperation patients were statistically significantly lower (p = 0.021  p = 0.043). The mean PMA between the ex and recovered patients were statistically significantly lower (p = 0.001, p = 0.001, p < 0.001). Dyspnoea, renal insufficiency, COPD, transfusion rate, operation rate, ventilator needy, and mean duration of hospitalization were statistically significant higher in patients with exitus. There is a significant difference in operation types, anesthesia type, and clinic rates. CONCLUSION: Our data suggest that sarcopenia can be used to risk stratification in ICU patients. Future studies may use this technique to individualize postoperative interventions that may reduce the risk for an adverse discharge disposition related to critical illness, such as early mobilization, optimized nutritional support, and reduction of sedation and opioid dose. Hindawi 2018-02-12 /pmc/articles/PMC5896340/ /pubmed/29789798 http://dx.doi.org/10.1155/2018/5263208 Text en Copyright © 2018 Mehmet Toptas et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Toptas, Mehmet
Yalcin, Mazhar
Akkoc, İbrahim
Demir, Eren
Metin, Cagatay
Savas, Yildiray
Kalyoncuoglu, Muhsin
Can, Mehmet Mustafa
The Relation between Sarcopenia and Mortality in Patients at Intensive Care Unit
title The Relation between Sarcopenia and Mortality in Patients at Intensive Care Unit
title_full The Relation between Sarcopenia and Mortality in Patients at Intensive Care Unit
title_fullStr The Relation between Sarcopenia and Mortality in Patients at Intensive Care Unit
title_full_unstemmed The Relation between Sarcopenia and Mortality in Patients at Intensive Care Unit
title_short The Relation between Sarcopenia and Mortality in Patients at Intensive Care Unit
title_sort relation between sarcopenia and mortality in patients at intensive care unit
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896340/
https://www.ncbi.nlm.nih.gov/pubmed/29789798
http://dx.doi.org/10.1155/2018/5263208
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