Assays for Qualification and Quality Stratification of Clinical Biospecimens Used in Research: A Technical Report from the ISBER Biospecimen Science Working Group

This technical report presents quality control (QC) assays that can be performed in order to qualify clinical biospecimens that have been biobanked for use in research. Some QC assays are specific to a disease area. Some QC assays are specific to a particular downstream analytical platform. When suc...

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Detalles Bibliográficos
Autores principales: Betsou, Fay, Bulla, Alexandre, Cho, Sang Yun, Clements, Judith, Chuaqui, Rodrigo, Coppola, Domenico, De Souza, Yvonne, De Wilde, Annemieke, Grizzle, William, Guadagni, Fiorella, Gunter, Elaine, Heil, Stacey, Hodgkinson, Verity, Kessler, Joseph, Kiehntopf, Michael, Kim, Hee Sung, Koppandi, Iren, Shea, Katheryn, Singh, Rajeev, Sobel, Marc, Somiari, Stella, Spyropoulos, Demetri, Stone, Mars, Tybring, Gunnel, Valyi-Nagy, Klara, Van den Eynden, Gert, Wadhwa, Lalita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896556/
https://www.ncbi.nlm.nih.gov/pubmed/27046294
http://dx.doi.org/10.1089/bio.2016.0018
Descripción
Sumario:This technical report presents quality control (QC) assays that can be performed in order to qualify clinical biospecimens that have been biobanked for use in research. Some QC assays are specific to a disease area. Some QC assays are specific to a particular downstream analytical platform. When such a qualification is not possible, QC assays are presented that can be performed to stratify clinical biospecimens according to their biomolecular quality.

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