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Assays for Qualification and Quality Stratification of Clinical Biospecimens Used in Research: A Technical Report from the ISBER Biospecimen Science Working Group
This technical report presents quality control (QC) assays that can be performed in order to qualify clinical biospecimens that have been biobanked for use in research. Some QC assays are specific to a disease area. Some QC assays are specific to a particular downstream analytical platform. When suc...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896556/ https://www.ncbi.nlm.nih.gov/pubmed/27046294 http://dx.doi.org/10.1089/bio.2016.0018 |
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author | Betsou, Fay Bulla, Alexandre Cho, Sang Yun Clements, Judith Chuaqui, Rodrigo Coppola, Domenico De Souza, Yvonne De Wilde, Annemieke Grizzle, William Guadagni, Fiorella Gunter, Elaine Heil, Stacey Hodgkinson, Verity Kessler, Joseph Kiehntopf, Michael Kim, Hee Sung Koppandi, Iren Shea, Katheryn Singh, Rajeev Sobel, Marc Somiari, Stella Spyropoulos, Demetri Stone, Mars Tybring, Gunnel Valyi-Nagy, Klara Van den Eynden, Gert Wadhwa, Lalita |
author_facet | Betsou, Fay Bulla, Alexandre Cho, Sang Yun Clements, Judith Chuaqui, Rodrigo Coppola, Domenico De Souza, Yvonne De Wilde, Annemieke Grizzle, William Guadagni, Fiorella Gunter, Elaine Heil, Stacey Hodgkinson, Verity Kessler, Joseph Kiehntopf, Michael Kim, Hee Sung Koppandi, Iren Shea, Katheryn Singh, Rajeev Sobel, Marc Somiari, Stella Spyropoulos, Demetri Stone, Mars Tybring, Gunnel Valyi-Nagy, Klara Van den Eynden, Gert Wadhwa, Lalita |
author_sort | Betsou, Fay |
collection | PubMed |
description | This technical report presents quality control (QC) assays that can be performed in order to qualify clinical biospecimens that have been biobanked for use in research. Some QC assays are specific to a disease area. Some QC assays are specific to a particular downstream analytical platform. When such a qualification is not possible, QC assays are presented that can be performed to stratify clinical biospecimens according to their biomolecular quality. |
format | Online Article Text |
id | pubmed-5896556 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Mary Ann Liebert, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-58965562018-04-13 Assays for Qualification and Quality Stratification of Clinical Biospecimens Used in Research: A Technical Report from the ISBER Biospecimen Science Working Group Betsou, Fay Bulla, Alexandre Cho, Sang Yun Clements, Judith Chuaqui, Rodrigo Coppola, Domenico De Souza, Yvonne De Wilde, Annemieke Grizzle, William Guadagni, Fiorella Gunter, Elaine Heil, Stacey Hodgkinson, Verity Kessler, Joseph Kiehntopf, Michael Kim, Hee Sung Koppandi, Iren Shea, Katheryn Singh, Rajeev Sobel, Marc Somiari, Stella Spyropoulos, Demetri Stone, Mars Tybring, Gunnel Valyi-Nagy, Klara Van den Eynden, Gert Wadhwa, Lalita Biopreserv Biobank Original Articles This technical report presents quality control (QC) assays that can be performed in order to qualify clinical biospecimens that have been biobanked for use in research. Some QC assays are specific to a disease area. Some QC assays are specific to a particular downstream analytical platform. When such a qualification is not possible, QC assays are presented that can be performed to stratify clinical biospecimens according to their biomolecular quality. Mary Ann Liebert, Inc. 2016-10-01 2016-10-01 /pmc/articles/PMC5896556/ /pubmed/27046294 http://dx.doi.org/10.1089/bio.2016.0018 Text en © Fay Betsou et al., 2016; Published by Mary Ann Liebert, Inc. This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Articles Betsou, Fay Bulla, Alexandre Cho, Sang Yun Clements, Judith Chuaqui, Rodrigo Coppola, Domenico De Souza, Yvonne De Wilde, Annemieke Grizzle, William Guadagni, Fiorella Gunter, Elaine Heil, Stacey Hodgkinson, Verity Kessler, Joseph Kiehntopf, Michael Kim, Hee Sung Koppandi, Iren Shea, Katheryn Singh, Rajeev Sobel, Marc Somiari, Stella Spyropoulos, Demetri Stone, Mars Tybring, Gunnel Valyi-Nagy, Klara Van den Eynden, Gert Wadhwa, Lalita Assays for Qualification and Quality Stratification of Clinical Biospecimens Used in Research: A Technical Report from the ISBER Biospecimen Science Working Group |
title | Assays for Qualification and Quality Stratification of Clinical Biospecimens Used in Research: A Technical Report from the ISBER Biospecimen Science Working Group |
title_full | Assays for Qualification and Quality Stratification of Clinical Biospecimens Used in Research: A Technical Report from the ISBER Biospecimen Science Working Group |
title_fullStr | Assays for Qualification and Quality Stratification of Clinical Biospecimens Used in Research: A Technical Report from the ISBER Biospecimen Science Working Group |
title_full_unstemmed | Assays for Qualification and Quality Stratification of Clinical Biospecimens Used in Research: A Technical Report from the ISBER Biospecimen Science Working Group |
title_short | Assays for Qualification and Quality Stratification of Clinical Biospecimens Used in Research: A Technical Report from the ISBER Biospecimen Science Working Group |
title_sort | assays for qualification and quality stratification of clinical biospecimens used in research: a technical report from the isber biospecimen science working group |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896556/ https://www.ncbi.nlm.nih.gov/pubmed/27046294 http://dx.doi.org/10.1089/bio.2016.0018 |
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