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Assays for Qualification and Quality Stratification of Clinical Biospecimens Used in Research: A Technical Report from the ISBER Biospecimen Science Working Group

This technical report presents quality control (QC) assays that can be performed in order to qualify clinical biospecimens that have been biobanked for use in research. Some QC assays are specific to a disease area. Some QC assays are specific to a particular downstream analytical platform. When suc...

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Autores principales: Betsou, Fay, Bulla, Alexandre, Cho, Sang Yun, Clements, Judith, Chuaqui, Rodrigo, Coppola, Domenico, De Souza, Yvonne, De Wilde, Annemieke, Grizzle, William, Guadagni, Fiorella, Gunter, Elaine, Heil, Stacey, Hodgkinson, Verity, Kessler, Joseph, Kiehntopf, Michael, Kim, Hee Sung, Koppandi, Iren, Shea, Katheryn, Singh, Rajeev, Sobel, Marc, Somiari, Stella, Spyropoulos, Demetri, Stone, Mars, Tybring, Gunnel, Valyi-Nagy, Klara, Van den Eynden, Gert, Wadhwa, Lalita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896556/
https://www.ncbi.nlm.nih.gov/pubmed/27046294
http://dx.doi.org/10.1089/bio.2016.0018
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author Betsou, Fay
Bulla, Alexandre
Cho, Sang Yun
Clements, Judith
Chuaqui, Rodrigo
Coppola, Domenico
De Souza, Yvonne
De Wilde, Annemieke
Grizzle, William
Guadagni, Fiorella
Gunter, Elaine
Heil, Stacey
Hodgkinson, Verity
Kessler, Joseph
Kiehntopf, Michael
Kim, Hee Sung
Koppandi, Iren
Shea, Katheryn
Singh, Rajeev
Sobel, Marc
Somiari, Stella
Spyropoulos, Demetri
Stone, Mars
Tybring, Gunnel
Valyi-Nagy, Klara
Van den Eynden, Gert
Wadhwa, Lalita
author_facet Betsou, Fay
Bulla, Alexandre
Cho, Sang Yun
Clements, Judith
Chuaqui, Rodrigo
Coppola, Domenico
De Souza, Yvonne
De Wilde, Annemieke
Grizzle, William
Guadagni, Fiorella
Gunter, Elaine
Heil, Stacey
Hodgkinson, Verity
Kessler, Joseph
Kiehntopf, Michael
Kim, Hee Sung
Koppandi, Iren
Shea, Katheryn
Singh, Rajeev
Sobel, Marc
Somiari, Stella
Spyropoulos, Demetri
Stone, Mars
Tybring, Gunnel
Valyi-Nagy, Klara
Van den Eynden, Gert
Wadhwa, Lalita
author_sort Betsou, Fay
collection PubMed
description This technical report presents quality control (QC) assays that can be performed in order to qualify clinical biospecimens that have been biobanked for use in research. Some QC assays are specific to a disease area. Some QC assays are specific to a particular downstream analytical platform. When such a qualification is not possible, QC assays are presented that can be performed to stratify clinical biospecimens according to their biomolecular quality.
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spelling pubmed-58965562018-04-13 Assays for Qualification and Quality Stratification of Clinical Biospecimens Used in Research: A Technical Report from the ISBER Biospecimen Science Working Group Betsou, Fay Bulla, Alexandre Cho, Sang Yun Clements, Judith Chuaqui, Rodrigo Coppola, Domenico De Souza, Yvonne De Wilde, Annemieke Grizzle, William Guadagni, Fiorella Gunter, Elaine Heil, Stacey Hodgkinson, Verity Kessler, Joseph Kiehntopf, Michael Kim, Hee Sung Koppandi, Iren Shea, Katheryn Singh, Rajeev Sobel, Marc Somiari, Stella Spyropoulos, Demetri Stone, Mars Tybring, Gunnel Valyi-Nagy, Klara Van den Eynden, Gert Wadhwa, Lalita Biopreserv Biobank Original Articles This technical report presents quality control (QC) assays that can be performed in order to qualify clinical biospecimens that have been biobanked for use in research. Some QC assays are specific to a disease area. Some QC assays are specific to a particular downstream analytical platform. When such a qualification is not possible, QC assays are presented that can be performed to stratify clinical biospecimens according to their biomolecular quality. Mary Ann Liebert, Inc. 2016-10-01 2016-10-01 /pmc/articles/PMC5896556/ /pubmed/27046294 http://dx.doi.org/10.1089/bio.2016.0018 Text en © Fay Betsou et al., 2016; Published by Mary Ann Liebert, Inc. This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Betsou, Fay
Bulla, Alexandre
Cho, Sang Yun
Clements, Judith
Chuaqui, Rodrigo
Coppola, Domenico
De Souza, Yvonne
De Wilde, Annemieke
Grizzle, William
Guadagni, Fiorella
Gunter, Elaine
Heil, Stacey
Hodgkinson, Verity
Kessler, Joseph
Kiehntopf, Michael
Kim, Hee Sung
Koppandi, Iren
Shea, Katheryn
Singh, Rajeev
Sobel, Marc
Somiari, Stella
Spyropoulos, Demetri
Stone, Mars
Tybring, Gunnel
Valyi-Nagy, Klara
Van den Eynden, Gert
Wadhwa, Lalita
Assays for Qualification and Quality Stratification of Clinical Biospecimens Used in Research: A Technical Report from the ISBER Biospecimen Science Working Group
title Assays for Qualification and Quality Stratification of Clinical Biospecimens Used in Research: A Technical Report from the ISBER Biospecimen Science Working Group
title_full Assays for Qualification and Quality Stratification of Clinical Biospecimens Used in Research: A Technical Report from the ISBER Biospecimen Science Working Group
title_fullStr Assays for Qualification and Quality Stratification of Clinical Biospecimens Used in Research: A Technical Report from the ISBER Biospecimen Science Working Group
title_full_unstemmed Assays for Qualification and Quality Stratification of Clinical Biospecimens Used in Research: A Technical Report from the ISBER Biospecimen Science Working Group
title_short Assays for Qualification and Quality Stratification of Clinical Biospecimens Used in Research: A Technical Report from the ISBER Biospecimen Science Working Group
title_sort assays for qualification and quality stratification of clinical biospecimens used in research: a technical report from the isber biospecimen science working group
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896556/
https://www.ncbi.nlm.nih.gov/pubmed/27046294
http://dx.doi.org/10.1089/bio.2016.0018
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