Cargando…
Inhibition of NIPBL enhances the chemosensitivity of non-small-cell lung cancer cells via the DNA damage response and autophagy pathway
BACKGROUND: Previously, we reported that high expression of nipped-B-like protein (NIPBL) was strongly correlated with poor prognosis, tumor differentiation, and lymph node metastasis. Survival analysis indicated that NIPBL expression was a potential prognostic factor for non-small cell lung cancer...
Autores principales: | Zheng, Lei, Zhou, Huanhuan, Guo, Liwei, Xu, Xiaoling, Zhang, Shengjie, Xu, Weizhen, Mao, Weimin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896680/ https://www.ncbi.nlm.nih.gov/pubmed/29670369 http://dx.doi.org/10.2147/OTT.S158655 |
Ejemplares similares
-
Enhanced expression of cohesin loading factor NIPBL confers poor prognosis and chemotherapy resistance in non-small cell lung cancer
por: Xu, Weizhen, et al.
Publicado: (2015) -
Downregulation of Cohesin Loading Factor Nipped-B-Like Protein (NIPBL) Induces Cell Cycle Arrest, Apoptosis, and Autophagy of Breast Cancer Cell Lines
por: Zhou, Huanhuan, et al.
Publicado: (2017) -
Independent mechanisms recruit the cohesin loader protein NIPBL to sites of DNA damage
por: Bot, Christopher, et al.
Publicado: (2017) -
The Cohesin loading factor NIPBL recruits histone deacetylases to mediate local chromatin modifications
por: Jahnke, Philipp, et al.
Publicado: (2008) -
Transcriptional Dysregulation in NIPBL and Cohesin Mutant Human Cells
por: Liu, Jinglan, et al.
Publicado: (2009)