X-ray structure and inhibition of the feline infectious peritonitis virus 3C-like protease: Structural implications for drug design

Feline infectious peritonitis (FIP) is a deadly disease that effects both domestic and wild cats and is caused by a mutation in feline coronavirus (FCoV) that allows the virus to replicate in macrophages. Currently, there are no treatments or vaccines available for the treatment of FIP even though i...

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Detalles Bibliográficos
Autores principales: St. John, Sarah E., Therkelsen, Matthew D., Nyalapatla, Prasanth R., Osswald, Heather L., Ghosh, Arun K., Mesecar, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896745/
https://www.ncbi.nlm.nih.gov/pubmed/26592814
http://dx.doi.org/10.1016/j.bmcl.2015.10.023

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