Cargando…
C. elegans MRP-5 Exports Vitamin B12 from Mother to Offspring to Support Embryonic Development
Vitamin B12 functions as a cofactor for methionine synthase to produce the anabolic methyl donor S-adenosylmethionine (SAM) and for methylmalonyl-CoA mutase to catabolize the short-chain fatty acid propionate. In the nematode Caenorhabditis elegans, maternally supplied vitamin B12 is required for th...
Autores principales: | Na, Huimin, Ponomarova, Olga, Giese, Gabrielle E., Walhout, Albertha J.M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896776/ https://www.ncbi.nlm.nih.gov/pubmed/29562169 http://dx.doi.org/10.1016/j.celrep.2018.02.100 |
Ejemplares similares
-
Caenorhabditis elegans methionine/S-adenosylmethionine cycle activity is sensed and adjusted by a nuclear hormone receptor
por: Giese, Gabrielle E, et al.
Publicado: (2020) -
WormPaths: Caenorhabditis elegans metabolic pathway annotation and visualization
por: Walker, Melissa D., et al.
Publicado: (2020) -
A D-2-hydroxyglutarate dehydrogenase mutant reveals a critical role for ketone body metabolism in Caenorhabditis elegans development
por: Ponomarova, Olga, et al.
Publicado: (2023) -
A metabolic regulatory network for the Caenorhabditis elegans intestine
por: Bhattacharya, Sushila, et al.
Publicado: (2022) -
Metabolic network rewiring of propionate flux compensates vitamin B12 deficiency in C. elegans
por: Watson, Emma, et al.
Publicado: (2016)