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The genetic landscape of a physical interaction

A key question in human genetics and evolutionary biology is how mutations in different genes combine to alter phenotypes. Efforts to systematically map genetic interactions have mostly made use of gene deletions. However, most genetic variation consists of point mutations of diverse and difficult t...

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Detalles Bibliográficos
Autores principales: Diss, Guillaume, Lehner, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896888/
https://www.ncbi.nlm.nih.gov/pubmed/29638215
http://dx.doi.org/10.7554/eLife.32472