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The genetic landscape of a physical interaction
A key question in human genetics and evolutionary biology is how mutations in different genes combine to alter phenotypes. Efforts to systematically map genetic interactions have mostly made use of gene deletions. However, most genetic variation consists of point mutations of diverse and difficult t...
Autores principales: | Diss, Guillaume, Lehner, Ben |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896888/ https://www.ncbi.nlm.nih.gov/pubmed/29638215 http://dx.doi.org/10.7554/eLife.32472 |
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