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New insights into the transposition mechanisms of IS6110 and its dynamic distribution between Mycobacterium tuberculosis Complex lineages

The insertion Sequence IS6110, only present in the pathogens of the Mycobacterium tuberculosis Complex (MTBC), has been the gold-standard epidemiological marker for TB for more than 25 years, but biological implications of IS6110 transposition during MTBC adaptation to humans remain elusive. By stud...

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Detalles Bibliográficos
Autores principales: Gonzalo-Asensio, Jesús, Pérez, Irene, Aguiló, Nacho, Uranga, Santiago, Picó, Ana, Lampreave, Carlos, Cebollada, Alberto, Otal, Isabel, Samper, Sofía, Martín, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896891/
https://www.ncbi.nlm.nih.gov/pubmed/29649213
http://dx.doi.org/10.1371/journal.pgen.1007282