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Generation of multidrug resistant human tissues by overexpression of the ABCG2 multidrug transporter in embryonic stem cells

The ABCG2 multidrug transporter provides resistance against various endo- and xenobiotics, and protects the stem cells against toxins and stress conditions. We have shown earlier that a GFP-tagged version of ABCG2 is fully functional and may be used to follow the expression, localization and functio...

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Detalles Bibliográficos
Autores principales: Erdei, Zsuzsa, Schamberger, Anita, Török, György, Szebényi, Kornélia, Várady, György, Orbán, Tamás I., Homolya, László, Sarkadi, Balázs, Apáti, Ágota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896897/
https://www.ncbi.nlm.nih.gov/pubmed/29649238
http://dx.doi.org/10.1371/journal.pone.0194925