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Generation of multidrug resistant human tissues by overexpression of the ABCG2 multidrug transporter in embryonic stem cells
The ABCG2 multidrug transporter provides resistance against various endo- and xenobiotics, and protects the stem cells against toxins and stress conditions. We have shown earlier that a GFP-tagged version of ABCG2 is fully functional and may be used to follow the expression, localization and functio...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896897/ https://www.ncbi.nlm.nih.gov/pubmed/29649238 http://dx.doi.org/10.1371/journal.pone.0194925 |