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Common and divergent features of galactose-1-phosphate and fructose-1-phosphate toxicity in yeast
Toxicity resulting from accumulation of sugar-phosphate molecules is an evolutionarily conserved phenomenon, observed in multiple bacterial and eukaryotic systems, including a number of human diseases. However, the molecular mechanisms involved in sugar-phosphate toxicity remain unclear. Using the m...
Autores principales: | Gibney, Patrick A., Schieler, Ariel, Chen, Jonathan C., Bacha-Hummel, Jessie M., Botstein, Maxim, Volpe, Matthew, Silverman, Sanford J., Xu, Yifan, Bennett, Bryson D., Rabinowitz, Joshua D., Botstein, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896929/ https://www.ncbi.nlm.nih.gov/pubmed/29444955 http://dx.doi.org/10.1091/mbc.E17-11-0666 |
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