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Inducing cell death in vitro in cancer cells by targeted delivery of cytochrome c via a transferrin conjugate

One of the major drawbacks of many of the currently used cancer drugs are off-target effects. Targeted delivery is one method to minimize such unwanted and detrimental events. To actively target lung cancer cells, we have developed a conjugate of the apoptosis inducing protein cytochrome c with tran...

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Detalles Bibliográficos
Autores principales: Saxena, Manoj, Delgado, Yamixa, Sharma, Rohit Kumar, Sharma, Shweta, Guzmán, Solimar Liz Ponce De León, Tinoco, Arthur D., Griebenow, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896948/
https://www.ncbi.nlm.nih.gov/pubmed/29649293
http://dx.doi.org/10.1371/journal.pone.0195542