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ICE1 promotes the link between splicing and nonsense-mediated mRNA decay

The nonsense-mediated mRNA decay (NMD) pathway detects aberrant transcripts containing premature termination codons (PTCs) and regulates expression of 5–10% of non-aberrant human mRNAs. To date, most proteins involved in NMD have been identified by genetic screens in model organisms; however, the in...

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Detalles Bibliográficos
Autores principales:	Baird, Thomas D, Cheng, Ken Chih-Chien, Chen, Yu-Chi, Buehler, Eugen, Martin, Scott E, Inglese, James, Hogg, J Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2018
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896957/ https://www.ncbi.nlm.nih.gov/pubmed/29528287 http://dx.doi.org/10.7554/eLife.33178

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