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Unraveling endothelin-1 induced hypercontractility of human pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension

Contraction of human pulmonary artery smooth muscle cells (HPASMC) isolated from pulmonary arterial hypertensive (PAH) and normal (non-PAH) subject lungs was determined and measured with real-time electrical impedance. Treatment of HPASMC with vasoactive peptides, endothelin-1 (ET-1) and bradykinin...

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Detalles Bibliográficos
Autores principales: Wilson, Jamie L., Warburton, Rod, Taylor, Linda, Toksoz, Deniz, Hill, Nicholas, Polgar, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897024/
https://www.ncbi.nlm.nih.gov/pubmed/29649319
http://dx.doi.org/10.1371/journal.pone.0195780

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