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Unraveling endothelin-1 induced hypercontractility of human pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension
Contraction of human pulmonary artery smooth muscle cells (HPASMC) isolated from pulmonary arterial hypertensive (PAH) and normal (non-PAH) subject lungs was determined and measured with real-time electrical impedance. Treatment of HPASMC with vasoactive peptides, endothelin-1 (ET-1) and bradykinin...
Autores principales: | Wilson, Jamie L., Warburton, Rod, Taylor, Linda, Toksoz, Deniz, Hill, Nicholas, Polgar, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897024/ https://www.ncbi.nlm.nih.gov/pubmed/29649319 http://dx.doi.org/10.1371/journal.pone.0195780 |
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