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FIGL1 and its novel partner FLIP form a conserved complex that regulates homologous recombination
Homologous recombination is central to repair DNA double-strand breaks, either accidently arising in mitotic cells or in a programed manner at meiosis. Crossovers resulting from the repair of meiotic breaks are essential for proper chromosome segregation and increase genetic diversity of the progeny...
Autores principales: | Fernandes, Joiselle Blanche, Duhamel, Marine, Seguéla-Arnaud, Mathilde, Froger, Nicole, Girard, Chloé, Choinard, Sandrine, Solier, Victor, De Winne, Nancy, De Jaeger, Geert, Gevaert, Kris, Andrey, Philippe, Grelon, Mathilde, Guerois, Raphael, Kumar, Rajeev, Mercier, Raphaël |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897033/ https://www.ncbi.nlm.nih.gov/pubmed/29608566 http://dx.doi.org/10.1371/journal.pgen.1007317 |
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