Integrin-based diffusion barrier separates membrane domains enabling the formation of microbiostatic frustrated phagosomes

Candida albicans hyphae can reach enormous lengths, precluding their internalization by phagocytes. Nevertheless, macrophages engulf a portion of the hypha, generating incompletely sealed tubular phagosomes. These frustrated phagosomes are stabilized by a thick cuff of F-actin that polymerizes in re...

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Detalles Bibliográficos
Autores principales: Maxson, Michelle E, Naj, Xenia, O'Meara, Teresa R, Plumb, Jonathan D, Cowen, Leah E, Grinstein, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897098/
https://www.ncbi.nlm.nih.gov/pubmed/29553370
http://dx.doi.org/10.7554/eLife.34798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897098/
https://www.ncbi.nlm.nih.gov/pubmed/29553370
http://dx.doi.org/10.7554/eLife.34798

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