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Phosphatase activity tunes two-component system sensor detection threshold
Two-component systems (TCSs) are the largest family of multi-step signal transduction pathways in biology, and a major source of sensors for biotechnology. However, the input concentrations to which biosensors respond are often mismatched with application requirements. Here, we utilize a mathematica...
Autores principales: | Landry, Brian P., Palanki, Rohan, Dyulgyarov, Nikola, Hartsough, Lucas A., Tabor, Jeffrey J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897336/ https://www.ncbi.nlm.nih.gov/pubmed/29650958 http://dx.doi.org/10.1038/s41467-018-03929-y |
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