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Validation of ultrasound bioimaging to predict worm burden and treatment efficacy in preclinical filariasis drug screening models
Filariasis is a global health problem targeted for elimination. Curative drugs (macrofilaricides) are required to accelerate elimination. Candidate macrofilaricides require testing in preclinical models of filariasis. The incidence of infection failures and high intra-group variation means that larg...
Autores principales: | Marriott, Amy E., Sjoberg, Hanna, Tyrer, Hayley, Gamble, Joanne, Murphy, Emma, Archer, John, Steven, Andrew, Taylor, Mark J., Turner, Joseph D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897408/ https://www.ncbi.nlm.nih.gov/pubmed/29651095 http://dx.doi.org/10.1038/s41598-018-24294-2 |
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