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Diverse Epitope Specificity, Immunodominance Hierarchy, and Functional Avidity of Effector CD4 T Cells Established During Priming Is Maintained in Lung After Influenza A Virus Infection
One of the major contributions to protective immunity to influenza viruses that is provided by virus-specific CD4 T cells is delivery of effector function to the infected lung. However, there is little known about the selection and breadth of viral epitope-specific CD4 T cells that home to the lung...
Autores principales: | Richards, Katherine A., DiPiazza, Anthony T., Rattan, Ajitanuj, Knowlden, Zackery A. G., Yang, Hongmei, Sant, Andrea J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897437/ https://www.ncbi.nlm.nih.gov/pubmed/29681900 http://dx.doi.org/10.3389/fimmu.2018.00655 |
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