Increased O-GlcNAcylation of Endothelial Nitric Oxide Synthase Compromises the Anti-contractile Properties of Perivascular Adipose Tissue in Metabolic Syndrome

Under physiological conditions, the perivascular adipose tissue (PVAT) negatively modulates vascular contractility. This property is lost in experimental and human obesity and in the metabolic syndrome, indicating that changes in PVAT function may contribute to vascular dysfunction associated with i...

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Detalles Bibliográficos
Autores principales: da Costa, Rafael M., da Silva, Josiane F., Alves, Juliano V., Dias, Thiago B., Rassi, Diane M., Garcia, Luis V., Lobato, Núbia de Souza, Tostes, Rita C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897513/
https://www.ncbi.nlm.nih.gov/pubmed/29681862
http://dx.doi.org/10.3389/fphys.2018.00341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897513/
https://www.ncbi.nlm.nih.gov/pubmed/29681862
http://dx.doi.org/10.3389/fphys.2018.00341

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