Cargando…

Overview on Clinical Relevance of Intra-Tumor Heterogeneity

Today, clinical evaluation of tumor heterogeneity is an emergent issue to improve clinical oncology. In particular, intra-tumor heterogeneity (ITH) is closely related to cancer progression, resistance to therapy, and recurrences. It is interconnected with complex molecular mechanisms including spati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Stanta, Giorgio, Bonin, Serena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897590/ https://www.ncbi.nlm.nih.gov/pubmed/29682505 http://dx.doi.org/10.3389/fmed.2018.00085

Ejemplares similares

Overview of Tumor Heterogeneity in High-Grade Serous Ovarian Cancers
por: Azzalini, Eros, et al.
Publicado: (2023)

A Practical Approach to the Diagnosis of Lyme Borreliosis: From Clinical Heterogeneity to Laboratory Methods
por: Trevisan, Giusto, et al.
Publicado: (2020)

Management of stage II colon cancer - the use of molecular biomarkers for adjuvant therapy decision
por: Donada, Marisa, et al.
Publicado: (2013)

The Role of Intra-Tumoral Heterogeneity and Its Clinical Relevance in Epithelial Ovarian Cancer Recurrence and Metastasis
por: Roberts, Cai M., et al.
Publicado: (2019)

Reliability of miRNA Analysis from Fixed and Paraffin-Embedded Tissues
por: Azzalini, Eros, et al.
Publicado: (2019)

Is Human Papillomavirus Associated with Prostate Cancer Survival?
por: Pascale, Mariarosa, et al.
Publicado: (2013)

Are Breast Cancer Molecular Classes Predictive of Survival in Patients with Long Follow-Up?
por: Pracella, Danae, et al.
Publicado: (2013)

Mutant Allele Frequency-Based Intra-Tumoral Genetic Heterogeneity Related to the Tumor Shrinkage Mode After Neoadjuvant Chemotherapy in Breast Cancer Patients
por: Zheng, Chun-hui, et al.
Publicado: (2021)

Editorial: Tumor Heterogeneity
por: La Rosa, Stefano, et al.
Publicado: (2019)

Reduced expression of α-L-Fucosidase-1 (FUCA-1) predicts recurrence and shorter cancer specific survival in luminal B LN+ breast cancer patients
por: Bonin, Serena, et al.
Publicado: (2018)

A Novel HPLC-Based Method to Investigate on RNA after Fixation
por: Fattorini, Paolo, et al.
Publicado: (2020)

Case Study: Intra-Patient Heterogeneity of Aneurysmal Tissue Properties
por: Martufi, Giampaolo, et al.
Publicado: (2018)

The human RECQ1 helicase is highly expressed in glioblastoma and plays an important role in tumor cell proliferation
por: Mendoza-Maldonado, Ramiro, et al.
Publicado: (2011)

Heterogeneity of the tumor immune microenvironment and its clinical relevance
por: Jia, Qingzhu, et al.
Publicado: (2022)

Mycosis fungoides: is it a Borrelia burgdorferi-associated disease?
por: Tothova, S Miertusova, et al.
Publicado: (2006)

Tumor Heterogeneity in Breast Cancer
por: Turashvili, Gulisa, et al.
Publicado: (2017)

Evaluation of Intra-Tumoral Vascularization in Hepatocellular Carcinomas
por: Zhang, Qi, et al.
Publicado: (2020)

Breast cancer intra-tumor heterogeneity
por: Martelotto, Luciano G, et al.
Publicado: (2014)

Collaborative intra-tumor heterogeneity detection
por: Khakabimamaghani, Sahand, et al.
Publicado: (2019)

Intra-tumor heterogeneity for endometrial cancer and its clinical significance
por: Yin, Fu-Fen, et al.
Publicado: (2019)

Intra-Tumor Genetic Heterogeneity in Wilms Tumor: Clonal Evolution and Clinical Implications
por: Cresswell, George D., et al.
Publicado: (2016)

Multi-Site Tumour Sampling Improves the Detection of Intra-Tumour Heterogeneity in Oral and Oropharyngeal Squamous Cell Carcinoma
por: Jie, Weiping, et al.
Publicado: (2021)

The proliferation marker Ki67, but not neuroendocrine expression, is an independent factor in the prediction of prognosis of primary prostate cancer patients
por: Pascale, Mariarosa, et al.
Publicado: (2016)

Intra-tumor heterogeneity: lessons from microbial evolution and clinical implications
por: de Bruin, Elza C, et al.
Publicado: (2013)

Intra-tumor heterogeneity in head and neck cancer and its clinical implications
por: Mroz, Edmund A., et al.
Publicado: (2016)

Intra-tumor Genetic Heterogeneity in Rectal Cancer
por: Hardiman, Karin M., et al.
Publicado: (2015)

Addressing intra-tumoral heterogeneity and therapy resistance
por: Rybinski, Brad, et al.
Publicado: (2016)

Allergic Rhinitis: A Clinical and Pathophysiological Overview
por: Nur Husna, Siti Muhamad, et al.
Publicado: (2022)

PI3K/AKT Signaling in Breast Cancer Molecular Subtyping and Lymph Node Involvement
por: Bonin, S., et al.
Publicado: (2019)

Dynamic Emergence of Observed and Hidden Intra-tumor Heterogeneity
por: Raynaud, Franck, et al.
Publicado: (2019)

epihet for intra-tumoral epigenetic heterogeneity analysis and visualization
por: Chen, Xiaowen, et al.
Publicado: (2021)

Simulating the Dynamic Intra-Tumor Heterogeneity and Therapeutic Responses
por: Liu, Yongjing, et al.
Publicado: (2022)

Gene expression-based dissection of inter-histotypes, intra-histotype and intra-tumor heterogeneity in pediatric tumors
por: Ciceri, Sara, et al.
Publicado: (2022)

Heterogeneity Mapping of Protein Expression in Tumors using Quantitative Immunofluorescence
por: Faratian, Dana, et al.
Publicado: (2011)

Clinical Overview of Progressive Fibrotic Interstitial Lung Disease
por: Case, Amy Hajari
Publicado: (2022)

AKT Isoforms Interplay in High-Grade Serous Ovarian Cancer Prognosis and Characterization
por: Azzalini, Eros, et al.
Publicado: (2022)

Spatial and temporal intra-tumoral heterogeneity in advanced HGSOC: Implications for surgical and clinical outcomes
por: Cunnea, Paula, et al.
Publicado: (2023)

Intra-patient intra-tumoral immune heterogeneity is evident at progression on targeted therapy and immunotherapy for melanoma
por: Reuben, Alexandre, et al.
Publicado: (2014)

Sundowning in Dementia: Clinical Relevance, Pathophysiological Determinants, and Therapeutic Approaches
por: Canevelli, Marco, et al.
Publicado: (2016)

Molecular Characterization and Clinical Relevance of ALDH2 in Human Cancers
por: Ma, Bo, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_vtn0cfqcp3nc6n5qamjcvd3fob