DuCLOX-2/5 Inhibition Attenuates Inflammatory Response and Induces Mitochondrial Apoptosis for Mammary Gland Chemoprevention

The present study is a pursuit to define implications of dual cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) (DuCLOX-2/5) inhibition on various aspects of cancer augmentation and chemoprevention. The monotherapy and combination therapy of zaltoprofen (COX-2 inhibitor) and zileuton (5-LOX inhibi...

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Detalles Bibliográficos
Autores principales: Gautam, Swetlana, Rawat, Atul K., Sammi, Shreesh R., Roy, Subhadeep, Singh, Manjari, Devi, Uma, Yadav, Rajnish K., Singh, Lakhveer, Rawat, Jitendra K., Ansari, Mohd N., Saeedan, Abdulaziz S., Kumar, Dinesh, Pandey, Rakesh, Kaithwas, Gaurav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897656/
https://www.ncbi.nlm.nih.gov/pubmed/29681851
http://dx.doi.org/10.3389/fphar.2018.00314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897656/
https://www.ncbi.nlm.nih.gov/pubmed/29681851
http://dx.doi.org/10.3389/fphar.2018.00314

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