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Resveratrol attenuates high glucose-induced nucleus pulposus cell apoptosis and senescence through activating the ROS-mediated PI3K/Akt pathway
Background: Diabetes mellitus is closely correlated with disc degeneration. Nucleus pulposus (NP) cell apoptosis and senescence are typical cellular features within the degenerative disc. Resveratrol is a newly identified phytoalexin that has protective effects on cartilaginous tissue. Objective: To...
Autores principales: | Wang, Wenping, Li, Pei, Xu, Jiagang, Wu, Xiangkun, Guo, Zhiliang, Fan, Lijing, Song, Ruipeng, Wang, Jianli, Wei, Li, Teng, Haijun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897744/ https://www.ncbi.nlm.nih.gov/pubmed/29273676 http://dx.doi.org/10.1042/BSR20171454 |
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