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Regulation of RNA polymerase II processivity by Spt5 is restricted to a narrow window during elongation

Spt5 is a highly conserved RNA polymerase II (Pol II)‐associated pausing and elongation factor. However, its impact on global elongation and Pol II processivity in mammalian cells has not been clarified. Here, we show that depleting Spt5 in mouse embryonic fibroblasts (MEFs) does not cause global el...

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Detalles Bibliográficos
Autores principales:	Fitz, Johanna, Neumann, Tobias, Pavri, Rushad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897773/ https://www.ncbi.nlm.nih.gov/pubmed/29514850 http://dx.doi.org/10.15252/embj.201797965

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