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Ebola Virus Ribonucleic Acid Detection in Semen More Than Two Years After Resolution of Acute Ebola Virus Infection

Among 149 men who survived Ebola virus disease (EVD) and donated semen 260–1016 days after EVD onset, Ebola virus (EBOV) ribonucleic acid (RNA) was detected in 13 (9%). Of 137 men who donated semen 2 years after EVD onset, 11 (8%) had an EBOV RNA-positive specimen. The mechanism underlying the persi...

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Detalles Bibliográficos
Autores principales: Fischer, William A, Brown, Jerry, Wohl, David Alain, Loftis, Amy James, Tozay, Sam, Reeves, Edwina, Pewu, Korto, Gorvego, Galapaki, Quellie, Saturday, Cunningham, Coleen K, Merenbloom, Carson, Napravnik, Sonia, Dube, Karine, Adjasoo, David, Jones, Erin, Bonarwolo, Korlia, Hoover, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897835/
https://www.ncbi.nlm.nih.gov/pubmed/29670927
http://dx.doi.org/10.1093/ofid/ofx155
Descripción
Sumario:Among 149 men who survived Ebola virus disease (EVD) and donated semen 260–1016 days after EVD onset, Ebola virus (EBOV) ribonucleic acid (RNA) was detected in 13 (9%). Of 137 men who donated semen 2 years after EVD onset, 11 (8%) had an EBOV RNA-positive specimen. The mechanism underlying the persistence of EBOV RNA in semen is unclear, and it is unclear whether the detection of viral RNA represents the presence of infectious virus.