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Proteome-wide mapping of PQS-interacting proteins in Pseudomonas aeruginosa

The opportunistic human pathogen Pseudomonas aeruginosa secretes 2-heptyl-3-hydroxy-4-quinolone (PQS), a quorum sensing (QS) signal that regulates the expression of numerous virulence genes. Here we report the development and application of chemical probes to globally map quinolone binding proteins....

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Detalles Bibliográficos
Autores principales:	Dandela, Rambabu, Mantin, Danielle, Cravatt, Benjamin F., Rayo, Josep, Meijler, Michael M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2018
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897874/ https://www.ncbi.nlm.nih.gov/pubmed/29719702 http://dx.doi.org/10.1039/c7sc04287f

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