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Asperphenamate biosynthesis reveals a novel two-module NRPS system to synthesize amino acid esters in fungi

Amino acid esters are a group of structurally diverse natural products with distinct activities. Some are synthesized through an inter-molecular esterification step catalysed by nonribosomal peptide synthetase (NRPS). In bacteria, the formation of the intra-molecular ester bond is usually catalysed...

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Detalles Bibliográficos
Autores principales: Li, Wei, Fan, Aili, Wang, Long, Zhang, Peng, Liu, Zhiguo, An, Zhiqiang, Yin, Wen-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897882/
https://www.ncbi.nlm.nih.gov/pubmed/29719714
http://dx.doi.org/10.1039/c7sc02396k

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