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Favorable outcome of patients with lung adenocarcinoma harboring POLE mutations and expressing high PD-L1
Mutations in polymerase ε (POLE) confer favorable prognosis and outcomes in various cancer types, but their role in non-small cell lung cancer (NSCLC) is unknown. Utilizing the data of 513 patients with adenocarcinoma (LUAD) and 497 patients with squamous cell carcinoma (LUSC) from The Cancer Genome...
Autores principales: | Liu, Liang, Ruiz, Jimmy, O’Neill, Stacey S., Grant, Stefan C., Petty, W. Jeffrey, Yang, Meng, Chen, Kexin, Topaloglu, Umit, Pasche, Boris, Zhang, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897927/ https://www.ncbi.nlm.nih.gov/pubmed/29650000 http://dx.doi.org/10.1186/s12943-018-0832-y |
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