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Enhanced stability of a chimeric hepatitis B core antigen virus-like-particle (HBcAg-VLP) by a C-terminal linker-hexahistidine-peptide
BACKGROUND: Virus-like-particles (VLPs) are attractive nanoparticulate scaffolds for broad applications in material/biological sciences and medicine. Prior their functionalization, specific adaptations have to be carried out. These adjustments frequently lead to disordered particles, but the particl...
Autores principales: | Schumacher, Jens, Bacic, Tijana, Staritzbichler, René, Daneschdar, Matin, Klamp, Thorsten, Arnold, Philipp, Jägle, Sabrina, Türeci, Özlem, Markl, Jürgen, Sahin, Ugur |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897928/ https://www.ncbi.nlm.nih.gov/pubmed/29653575 http://dx.doi.org/10.1186/s12951-018-0363-0 |
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