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Beclomethasone dipropionate and formoterol fumarate synergistically interact in hyperresponsive medium bronchi and small airways

BACKGROUND: Corticosteroids increase the expression of β(2)-adrenoceptors (β(2)-ARs) and protect them against down-regulation. Conversely, β(2)-AR agonists improve the anti-inflammatory action of corticosteroids. Nevertheless, it is still uncertain whether adding a long-acting β(2)-AR agonist (LABA)...

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Detalles Bibliográficos
Autores principales: Calzetta, Luigino, Matera, Maria Gabriella, Facciolo, Francesco, Cazzola, Mario, Rogliani, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897944/
https://www.ncbi.nlm.nih.gov/pubmed/29650006
http://dx.doi.org/10.1186/s12931-018-0770-7