Multicomponent polysaccharide–protein bioconjugation in the development of antibacterial glycoconjugate vaccine candidates

A new synthetic strategy for the development of multivalent antibacterial glycoconjugate vaccines is described. The approach comprises the utilization of an isocyanide-based multicomponent process for the conjugation of functionalized capsular polysaccharides of S. pneumoniae and S. Typhi to carrier...

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Detalles Bibliográficos
Autores principales: Méndez, Yanira, Chang, Janoi, Humpierre, Ana R., Zanuy, Abel, Garrido, Raine, Vasco, Aldrin V., Pedroso, Jessy, Santana, Darielys, Rodríguez, Laura M., García-Rivera, Dagmar, Valdés, Yury, Vérez-Bencomo, Vicente, Rivera, Daniel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897956/
https://www.ncbi.nlm.nih.gov/pubmed/29719713
http://dx.doi.org/10.1039/c7sc05467j

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